Health Economics & Outcomes Research

Evidence that
moves decisions.

Keystone Advisory delivers rigorous health economic analysis, outcomes research, and strategic counsel for life sciences organizations navigating complex payer and regulatory environments.

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About

Health economics done with rigor and intent.

Eric Stone
Eric Stone, MHSFounder
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Keystone Advisory is an independent health economics and outcomes research consultancy founded by Eric Stone, MHS. With deep expertise in cost-effectiveness modeling, real-world evidence, and health data strategy, Keystone helps life sciences organizations build the evidence base that matters to payers, regulators, and clinicians.

Grounded in academic rigor and sharpened through years of industry experience spanning health systems, technology, and pharma, Keystone delivers analysis that is transparent, defensible, and decision-ready.

MHS — Health Economics & Outcomes Research, Johns Hopkins Bloomberg School of Public Health
AB — University of Chicago
Penn Medicine · Jefferson Health · Leading health data companies
ISPOR presenter · Cost-effectiveness modeling · Real-world evidence
Services

Areas of expertise

01
Cost-Effectiveness & Economic Modeling

Decision-analytic models — Markov, partitioned survival, and beyond — built to withstand payer scrutiny and support submissions to HTA bodies, formulary committees, and health systems.

02
Real-World Evidence & Data Strategy

Study design, database selection, and analytical execution using claims, EHR, and registry data. End-to-end support from hypothesis formation through publication-ready outputs.

03
Health Economics Strategy & Advisory

Strategic counsel on evidence generation planning, market access positioning, value dossier development, and payer engagement — tailored to your asset’s stage and stakeholder landscape.

04
Systematic Literature Review

PRISMA-compliant literature reviews and evidence synthesis to map the clinical and economic evidence base, identify gaps, and support model inputs and value arguments.

05
Health Data Infrastructure

Expertise in real-world data assets, data operations, and analytics infrastructure. Advisory support for organizations building or scaling health data capabilities.

06
Publication & Scientific Communication

Manuscripts, abstracts, posters, and slide decks for ISPOR, AMCP, ASCO, and peer-reviewed journals. Clear, credible scientific storytelling for diverse audiences.

Selected Work

Publications, Projects & Presentations

2026 · ISPOR · Philadelphia, PA
Cost-Effectiveness Analysis of Allogeneic T-Regulatory Cell Therapy for Crohn’s Disease
ISPOR 2026 Annual Meeting — Poster Presentation
Cost-effectiveness
Real-World Evidence · Cardiology
Hospital Readmissions Analysis in Heart Failure
Real-world evidence study examining readmission drivers and outcomes — Jefferson Health
Real-world evidence
Real-World Evidence · Ophthalmology
NLP-Based Disease Characterization in Dry Eye
Real-world evidence analysis using large-scale EHR data — Verana Health
Real-world evidence
Health Systems · Clinical Informatics
EHR-Integrated Clinical Scheduling — Penn Medicine
Decision support and scheduling infrastructure within a large academic health system
Health systems
Ongoing · Advisory
Civic Executive Board — Strategic Advisory
Lebanon County, Pennsylvania
Advisory
Contact

Let’s work together.

Ready to build a stronger evidence base? Reach out.

Based in Philadelphia, PA
keystoneadv@proton.me
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